Confidence regions in Cox proportional hazards model with measurement errors and unbounded parameter set        
        
    
        Volume 5, Issue 1 (2018), pp. 37–52
            
    
                    Pub. online: 31 January 2018
                    
        Type: Research Article
            
                
             Open Access
Open Access
        
            
    
                Received
16 January 2018
                                    16 January 2018
                Revised
17 January 2018
                                    17 January 2018
                Accepted
17 January 2018
                                    17 January 2018
                Published
31 January 2018
                    31 January 2018
Abstract
Cox proportional hazards model with measurement errors is considered. In Kukush and Chernova (2017), we elaborated a simultaneous estimator of the baseline hazard rate $\lambda (\cdot )$ and the regression parameter β, with the unbounded parameter set $\varTheta =\varTheta _{\lambda }\times \varTheta _{\beta }$, where $\varTheta _{\lambda }$ is a closed convex subset of $C[0,\tau ]$ and $\varTheta _{\beta }$ is a compact set in ${\mathbb{R}}^{m}$. The estimator is consistent and asymptotically normal. In the present paper, we construct confidence intervals for integral functionals of $\lambda (\cdot )$ and a confidence region for β under restrictions on the error distribution. In particular, we handle the following cases: (a) the measurement error is bounded, (b) it is a normally distributed random vector, and (c) it has independent components which are shifted Poisson random variables.
            References
 Augustin, T.: An exact corrected log-likelihood function for Cox’s proportional hazards model under measurement error and some extensions. Scand. J. Statist. 31(1), 43–50 (2004). doi:https://doi.org/10.1111/j.1467-9469.2004.00371.x. MR2042597
 Chimisov, C., Kukush, A.: Asymptotic normality of corrected estimator in Cox proportional hazards model with measurement error. Mod. Stoch. Theory Appl. 1(1), 13–32 (2014). doi:https://doi.org/10.15559/vmsta-2014.1.1.3. MR3314791
 Cox, D.R.: Regression models and life tables (with discussion). Journal of the Royal Statistical Society, Series B 34, 187–220 (1972). MR0341758
 Földes, A., Rejtö, L.: Strong uniform consistency for nonparametric survival curve estimators from randomly censored data. Ann. Statist., 122–129 (1981). MR0600537
 Kukush, A., Baran, S., Fazekas, I., Usoltseva, E.: Simultaneous estimation of baseline hazard rate and regression parameters in Cox proportional hazards model with measurement error. J. Statist. Res. 45(2), 77 (2011). MR2934363
 Kukush, A., Chernova, O.: Consistent estimation in Cox proportional hazards model with measurement errors and unbounded parameter set. arXiv preprint arXiv:1703.10940 (2017). MR3666874
 Kukush, A., Chernova, O.: Consistent estimation in Cox proportional hazards model with measurement errors and unbounded parameter set (Ukrainian). Teor. Imovir. Mat. Stat. 96, 100–109 (2017). MR3666874
 Stefanski, L.A.: Unbiased estimation of a nonlinear function of a normal mean with application to measurement error models. Comm. Statist. Theory Methods 18(12), 4335–4358 (1990). MR1046712
 
            